Usability refers to a software product's capacity to be unstated, erudite and appealing to the user when used under convinced conditions. Human-computer interaction (HCI) is one of the most significant fields in usability. For the past few years, e-commerce has been a hot area. E-commerce is the practice of buying and selling products online. Many e-commerce businesses aim to build a following of devoted customers. Several elements affect e-commerce website success, but usability—or the website's usability—is a crucial component in online company success. The significance of evaluating the usability of e-commerce websites is well recognized, and this area of study attracted a lot of attention in the previous ten years. The main goals of the dissertation are to evaluate the usability of the e-commerce websites for Amazon, Flipkart, Alibaba, Daraz, and Walmart through survey evaluation, compare the usability using Nielson's usability heuristics to discover the most usable website among these E-commerce websites, and discover the most effective website between these E-commerce websites to complete tasks faster. This research aims to design, develop and evaluate a web base application related to E-Commerce to provide a better user experience. Here studied the most significant usability issues, according to HCI design patterns. The usability tests are run to see how users react to adaptive user interfaces and systems in terms of effectiveness, efficiency, and satisfaction. The usability of the e-commerce websites for Amazon, Flipkart, Alibaba, Daraz, and Walmart was evaluated by a survey, and the results were used to compare the usability of e-commerce websites. The users were given a list of six tasks, some of which included registering and placing an order for a product on five different e-commerce websites, and the time it acquired to complete those tasks was recorded. The average time needed to complete each job on these websites will be compared to determine whether an e-commerce site is more effective at completing tasks quickly. According to survey results and analysis results, Amazon is more useable than other e-commerce websites and offers greater efficiency to complete tasks in less time.