Manuscript Title:

IMPERIALIDIENE: NEW STEROIDAL ALKALOID PRODUCED BY MICROBIAL TRANSFORMATION OF IMPERIALINE, ISOLATION AND STRUCTURE ELUCIDATION

Author:

SHAIKH ZIAUDDIN SULTANI, MUHAMMAD SHAHAB ALAM, NUSRAT KIRAN, ZUBAIR HASHMI, MUHAMMAD AIJAZ ANWAR

DOI Number:

DOI:10.17605/OSF.IO/BZVGK

Published : 2022-11-10

About the author(s)

1. SHAIKH ZIAUDDIN SULTANI - Department of Chemistry, Government Degree Science and Commerce College, Landhi-Korangi, Karachi, Pakistan.
2. MUHAMMAD SHAHAB ALAM - Department of Basic Science Mathematics & Humanities, Dawood University of Engineering and Technology, New MA Jinnah road, Karachi, Pakistan.
3. NUSRAT KIRAN - Department of Chemical Engineering, Dawood University of Engineering and Technology, New MA Jinnah road, Karachi, Pakistan.
4. ZUBAIR HASHMI - Department of Chemical Engineering, Dawood University of Engineering and Technology, New MA Jinnah road, Karachi, Pakistan.
5. MUHAMMAD AIJAZ ANWAR - Pharmaceutical Research Center, Pakistan Council of Scientific and Industrial Research (PCSIR) Laboratories Complex Karachi, Pakistan.

Full Text : PDF

Abstract

Incubation of Imperialine (1) with the fungus Cephalosporium aphidicola yielded a new and a known compound. These compounds were fully Characterized and identified as ∆6,9(11), 5a, 17b, 25S-cevanin, 3b-20a-diol, named Imperialidiene (2), and Imperialone (3) on the basis of modern spectroscopic techniques.


Keywords

Cephalosporium Aphidicola, Imperialine, Imperialidiene, and Imperialone.